UQ researchers study phantom superbugs

University of Queensland researchers have discovered antibiotic-resistant bacteria in the Middle East which is cloaking itself in genetic material to avoid detection and placing the population at increased risk of deadly infections.

With the Middle East an increasingly popular destination for medical tourism and international workers seeking high-paying jobs, researchers warn the hard-to-detect superbugs may quickly spread beyond the region and emerge worldwide.
Researcher Hosam Mamoon Zowawi, from the UQ Centre for Clinical Research, said the “phantom” superbugs were found during a region-wide collaborative study on superbugs in the Gulf Cooperation Council (GCC) states of Saudi Arabia, United Arab Emirates, Kuwait, Qatar, Oman and Bahrain.
“The study found antibiotic-resistant bacteria in samples from all GCC states,” Mr Zowawi said.
“Not only were the bacteria widespread, but they were found to be carrying genetic material which empowers them to resist antibiotics and avoid detection in routine laboratory testing.
“This means patients are not being treated quickly with the right antibiotics, allowing the bacteria time to spread.
“The results of this study will hopefully encourage laboratories to introduce more specific testing techniques to identify and prevent overlooking the presence of phantom superbugs.
“Implementing effective infection control precautions is also essential to minimise the spread of superbugs.
“Several clusters of the phantom superbugs were also detected in different patients from the same hospitals, suggesting patient-to-patient spread of infection is occurring,” Mr Zowawi said.
The research team is now developing new diagnostic techniques to rapidly identify antibiotic-resistant bacteria, including the phantom superbug.
“We hope this will help in advancing the surveillance of superbugs by reducing the turnaround time to identify the deadly bacteria,” Mr Zowawi said.
“It will also assist clinicians to apply targeted treatment and implement infection control precautions sooner.”

UQ School of Chemistry and Molecular Biosciences

Situated within the Faculty of Science, the UQ School of Chemistry and Molecular Biosciences teaches and researches in the disciplines of Chemistry, Biochemistry, Biotechnology, Microbiology and Parasitology. The common thread in UQ’s discipline mix is the capacity of molecular-based approaches to create understanding and to lead to discovery. The school has a comprehensive array of scientific instrument installations, used by research staff and students and accessible in many cases to the wider university and public communities.
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