UQ science study reveals origins of blue eyes, lactose intolerance

4 March 2014

The discovery of a Stone Age man with the genes for blue eyes and dark skin has revealed that blue eye colour is likely to have spread through the European population earlier than fair skin.

University of Queensland Science
Some of UQ’s Science facilities

The discovery was made by an international team of researchers, including Associate Professor Rick Sturm from the University of Queensland’s Institute for Molecular Bioscience, who analyzed the genome from the tooth of a 7000-year-old human skeleton from Spain.
They were hoping to understand the evolutionary impact of early humans transitioning from hunter-gatherers to an agricultural society.
“Although these populations died out thousands of years ago, their genes have left clues to the way they looked and lived,” said Dr Sturm. “We found that the genes present in this Mesolithic man were likely to result in dark skin and dark hair, but blue eyes.
“This gene combination is unique and no longer exists in contemporary Europeans, suggesting that the spread of genes associated with a light eye colour may have occurred before the spread of genes for light skin.”
The team, led by researchers from the Institute of Evolutionary Biology in Spain and the University of Copenhagen in Denmark, also investigated genes associated with immunity and diet.
“This Mesolithic hunter-gatherer carried the gene for lactose-intolerance consistent with an inability to digest dairy products, and also saliva amylase genes indicative of a low-starch diet,” Dr Sturm said.
“This is in direct contrast to genomes from Neolithic farmers, who could process higher levels of lactose in milk and starch in grains.
“However, the genes for immunity to diseases were similar between the hunter-gatherer and farmers, suggesting that the transition to agriculture in European populations caused a change in diet but not immunity.”

UQ School of Chemistry and Molecular Biosciences

Situated within the Faculty of Science, the UQ School of Chemistry and Molecular Biosciences teaches and researches in the disciplines of Chemistry, Biochemistry, Biotechnology, Microbiology and Parasitology. The common thread in UQ’s discipline mix is the capacity of molecular-based approaches to create understanding and to lead to discovery. The school has a comprehensive array of scientific instrument installations, used by research staff and students and accessible in many cases to the wider university and public communities.
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